CENTRAL ANTICHOLINERGIC SYNDROME
DOI:
https://doi.org/10.32782/health-2023.2.9Keywords:
CAS, acetylcholine, cholinesterase, physostigmine.Abstract
The article addresses the problem of patient arousal disturbance after anesthesia, which is encountered in the practice of every anesthesiologist. This can manifest as psychomotor agitation, muscular tremor, or delayed arousal. In Germanspeaking countries, these states are combined into a single pathological syndrome called the Central Anticholinergic Syndrome (CAS). The frequency of CAS is approximately 10% during general anesthesia and 3.3% during regional anesthesia with sedation. In the intensive care unit, the syndrome is observed in approximately 5% of patients on mechanical ventilation. Spanish medical literature also periodically mentions CAS. English anesthesiologists, on the other hand, claim to rarely encounter this phenomenon. What is the reason for this correlation? It can be argued that the issue is not about the existence or absence of CAS, but about the analysis of symptoms during patient arousal and the approach to its management.
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URL: https://emedicine.medscape.com/article/812644-overview
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